Neutropenia, Thrombocytopenia or Other Cytopenias

Availability

North South North West Statewide

Pre-referral work-up

History

All referrals should comply to referral standards and include in particular:

  • Relevant investigations, including previous results to assess temporal pattern.

Tests

Full blood examination. Repeat investigation in case of processing error or transient cytopaenia

  • Cytopenias (neutropenia, thrombocytopenia) that are present on two separate occasions, at least one week apart, without other explanation are more likely to require investigation.

For isolated mild persistent cytopaenia, consider also:

  • Auto-immune screen, e.g. ANA, ENA, rheumatoid factor
  • Serum protein electrophoresis
  • Iron studies, B12, folate.

Interim/GP management

To refer a patient with this condition, please see the Haematology clinic page for the full referral process and templates.

For more information please see the Tasmanian Health Pathways website.

Emergency

Severe cytopenias if patient is unwell (i.e. infection, symptomatic anaemia, active bleeding):

  • Neutrophils < 0.5 x 10^9/L
  • Haemoglobin < 80g/L
  • Platelets <20 x 10^9/L

Blood film suggestive of thrombotic thrombocytopenic purpura (TTP/HUS)

Red flags are clinical indicators of possible serious underlying conditions requiring further medical intervention. They may or may not indicate an emergency.

Emergency:

Proceed to Emergency Department (ED). Please contact ED Medical Officer in Charge:
LGH ED – Phone: (03) 6777 6405  Fax: (03) 6777 5201
MCH ED – Phone: (03) 6478 5120  Fax: (03) 6441 5923
NWRH ED – Phone: (03) 6493 6340  Fax: (03) 6464 1926
RHH ED - Phone: (03) 6166 6100  Fax: (03) 6173 0489 - Discuss with the on call Haematologist/Registrar via switch (03) 6166 8308

Urgent:

Urgent Referrals generally need to be seen in the next one to two weeks

Please discuss these with the Haematology Registrar/Haematologist on call via switchboard on 6166 8308

Semi-urgent:

Triaged by medical staff and generally seen in the next six to eight weeks

Routine:

Triaged by medical staff and given the next available appointment